September 4, 2019
Nghiem P, Park SDownload PDF
Merkel cell carcinoma (MCC) is an aggressive skin cancer
that recurs in more than one-third of cases, with reported
mortality rates of 33%to 46%.1 Given this high risk
situation, MCC is often managed with therapies that
are aggressive and potentially toxic: extensive surgery,
radiation therapy (RT), and systemic therapy. Fortunately,
recent advances in multiple realms now allow
MCC management to be more effective and less toxic.
In this Viewpoint, we highlight 3 recent developments
relating to progress in local management, early detection
of recurrent disease, and systemic therapy. Although
it is not practical for physicians who rarely see
patients with MCC to remain up-to-date on the details
of management, herein we provide resources and guidelines
to help physicians ensure optimal initial care and
participate in longitudinal treatment of patients with
The authoritative source on Merkel cell carcinoma.
May 20, 2020
- What is a Merkel cell?
- What is Merkel cell carcinoma?
- Symptoms & appearance of Merkel cell carcinoma
- Causes of Merkel cell carcinoma
- Surgical excision
- Mohs micrographic surgery
- Radiation therapy
- Complementary & alternative therapies
- Clinical trials
- Adjuvant Avelumab in Merkel Cell Carcinoma Trial